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Cancer-linked protein binds to chromosome in unexpected way, study finds
A new 3D structure of a cancer-linked protein bound to its cellular partner reveals details of how the protein binds to chromosomes and could offer insights for future disease treatments.
Summary
A new 3D structure of a cancer-linked protein bound to its cellular partner reveals details of how the protein binds to chromosomes and could offer insights for future disease treatments. The protein—BRD4—plays a critical role in how cells read, copy and repair DNA and helps determine how different kinds of cells are made; it has been linked to many types of cancer and is considered a promising target for future therapies.
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