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Aspirin rarely used for colorectal cancer prevention
People with Lynch syndrome have a significantly increased risk of developing colorectal cancer and other types of cancer due to a hereditary predisposition.
AI Summary
People with Lynch syndrome face a markedly higher risk of colorectal and other cancers due to a hereditary predisposition. The earlier CAPP2 trial showed that a daily 600 mg dose of acetylsalicylic acid significantly lowered long‑term colorectal cancer risk in this group. New international CaPP3 research, published in The Lancet Gastroenterology & Hepatology, indicates that a much lower dose of 100 mg per day may provide a comparable preventive benefit while reducing side‑effects such as bleeding.
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