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An RNA molecule contributes to therapy resistance of triple negative breast cancer
Taiwan University Triple-negative breast cancer (TNBC) is the most aggressive type of breast cancer. Chemotherapy before or after surgery remains the standard treatment regimen for stage I–III TNBC.
AI Summary
Researchers found that a specific RNA molecule helps triple‑negative breast cancer cells resist chemotherapy. The study focused on stage I–III TNBC, where surgery and chemotherapy are standard, and noted that only a minority of patients respond to PARP‑inhibitor targeted therapy due to BRCA mutations.
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