An RNA molecule contributes to therapy resistance of triple negative… | HappeningNow.news

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An RNA molecule contributes to therapy resistance of triple negative breast cancer

Taiwan University Triple-negative breast cancer (TNBC) is the most aggressive type of breast cancer. Chemotherapy before or after surgery remains the standard treatment regimen for stage I–III TNBC.

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Researchers found that a specific RNA molecule helps triple‑negative breast cancer cells resist chemotherapy. The study focused on stage I–III TNBC, where surgery and chemotherapy are standard, and noted that only a minority of patients respond to PARP‑inhibitor targeted therapy due to BRCA mutations.

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