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Alzheimer's patients show elevated active meprin-β in brain and cerebrospinal fluid
A team from the Altered Molecular Mechanism in Alzheimer's Disease and Dementia laboratory, led by Javier Sáez Valero, a researcher at the Institute for Neurosciences (IN), a joint center of Miguel Hernández University of Elche (UMH) and…
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Researchers from the Altered Molecular Mechanism in Alzheimer’s Disease and Dementia laboratory, led by Javier Sáez Valero at the Institute for Neurosciences (a joint center of Miguel Hernández University of Elche and the Spanish National Research Council), have found that people with Alzheimer’s disease exhibit higher concentrations of the protein meprin‑β in both brain tissue and cerebrospinal fluid. The discovery was made by analyzing samples from Alzheimer’s patients, revealing a consistent elevation of active meprin‑β compared with non‑affected controls.
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