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After TAVI, anticoagulants outperform antiplatelet agents at preventing clots
DOI: 10.1001/jama.2026.17036 After transcatheter aortic valve implantation (TAVI), anticoagulation reduced imaging signs of clot formation on the new valve compared with antiplatelet therapy, without compromising safety.
AI Summary
The ACASA‑TAVI trial, presented at the ESC Congress 2026 and published in JAMA, found that after transcatheter aortic valve implantation, patients receiving anticoagulation therapy showed fewer imaging signs of clot formation on the new valve than those given antiplatelet therapy. The reduction in clot markers occurred without a compromise in safety outcomes. This result highlights a potential advantage of anticoagulants over antiplatelet agents in the post‑TAVI setting.
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