AI Summary

A new nanovesicle platform created at the Institute of Science Tokyo detects hydrostatic pressure by turning pressure‑induced molecular changes into fluorescent signals. The team engineered pyrene‑modified polyionic complex vesicles whose membrane stiffness determines pressure sensitivity. Softer vesicles respond strongly across a 0.1–50 MPa range, while stiffer vesicles exhibit pressure‑dependent shifts in fluorescence lifetime. This tunable approach links mechanical stiffness to optical readouts, enabling adjustable pressure sensing at the nanoscale.

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