Summary

Under the microscope, mitochondria inside healthy terminal Schwann cells form a web of interconnected branches, with tiny doughnut-shaped loops appearing near where the cells branch and split. But getting that view presents a challenge. Terminal Schwann cells—which help maintain and repair the connections between nerves and muscles—can begin changing shape the moment they are removed from their natural environment. That makes it difficult for scientists to study intracellular components as they would be in the body.

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