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A blood-based approach could enable personalized immunotherapy without the need for a tumor biopsy

In a study published in Cancer Discovery , cancer neoantigens and neoantigen-specific T cells were identified from patient blood samples by analyzing circulating tumor DNA (ctDNA) and immune cells.

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A study in Cancer Discovery identified cancer neoantigens and neoantigen‑specific T cells using circulating tumor DNA and immune cells from patient blood samples. The research was led by senior author Alena Gros, Ph.D., group leader of the Tumor Immunology and Immunotherapy Group at the Vall d’Hebron Institute of Oncology in Spain.

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