Summary

As mice age, their total egg reserve collapses around tenfold. Yet, according to a new study published in Nature Aging, the proportion of eggs in the brief window where a follicle is shifting from dormant to growing stays constant throughout life, at approximately 14%. "The same percentage of oocytes are being activated regardless of how old the mouse is. That means the ovary has a sensing mechanism that knows how many oocytes are in there and only awakens a fixed proportion.

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