AI Summary

A large study finds that about one‑quarter of depression cases are linked to disrupted circadian rhythms, a condition the researchers label “circadian depression.” This form of depression shows limited response to conventional antidepressant medication. The authors suggest that melatonin supplementation or behavioural approaches such as spending time outdoors in early‑morning sunlight may alleviate symptoms. The findings highlight a potential need for alternative treatment strategies targeting body‑clock alignment.

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